The Tour de France will pass over Westminster, Blackfriars and Tower Bridges in 2007.
Stage 1 ends at Canterbury.
"The Tour de France will be a huge boost to cycling and I very much welcome it," says Green Party London Assembly member Darren Johnson.
"However we need to make sure that the streets of London can not only accommodate world class cyclists for an international sporting event but can also accommodate ordinary cyclists every day of the year safely and efficiently.
"While much has been achieved over the last seven years in cutting the number of people killed or injured cycling in the capital, the 340 pedal cycle casualties in 2004 shows there is much still to do. Completing the London cycle network as soon as possible must be the top priority."
Initiatives to promote leisure and commuter cycling in London are likely to be bolted on to the Tour de France, with local groups such as Southwark Cyclists at the forefront.
• Full details of the Grand Depart can be found on the Tour de France London website.