Detectives have launched a murder investigation following the death of a young man after an altercation in Southwark Street early on Sunday morning.
A man in his early twenties was taken to Royal London Hospital suffering from head injuries; he died during the early hours of Monday.
An incident room has been opened under the command of Detective Chief Inspector Dave Manning from the homicide and serious crime command.
"At this early stage we believed the victim spent Saturday night/Sunday morning with friends in the club La Pollera Colora, London Bridge," says DCI Manning.
"It would appear that between 4am and 4.30am the victim and his friends were involved in some sort of disagreement with another group of people inside the club.
"A fracas broke out and the victim, with one of his friends, was ejected from the club by security. Shortly after he was attacked by a group of people on Southwark Street.
"Even though it was the early hours of Sunday, La Pollera Colora, Southwark Street and the general area would have been busy with people including night workers, commuters and revellers leaving the club.
"I am appealing to anyone who witnessed the altercation inside the club, or witnessed any part of the assault on Southwark Street, to contact the police. I would like to assure any witnesses that they will be treated with the utmost sensitivity."
Anyone with information is asked to contact the incident room on 020 8721 4054; if you wish to remain anonymous please call Crimestoppers on 0800 555 111.
Non-English speakers can speak to a translator by calling 0300 123 1212.
On Sunday four men were arrested on suspicion of murder. Two were later released with no further action; two remain in custody at south London police stations.