The relay race is open to a maximum of 25 teams from local businesses, each team consisting of four members.
Taking part this year is American personality Adam Richman who will be part of a team alongside Food Network chef Andy Bates.
Adam is in London promoting his new show 'Fandemonium'.
The winning team receives the Pancake Day Trophy to hold for a year along with a full Borough Market Kitchen Kit.
The event supports the work of the local Paintings in Hospitals charity, based at the Menier Gallery.