6.5 mile guided walk through Shad Thames, Rotherhithe, Surrey Docks and Deptford.
The route will take in the area's industrial past and how it has been transformed in recent years.
Packed lunch recommended or refreshments can be bought at the start of the walk or at Brunel Museum cafe.
Part of the Winter Wanders weekend organised by Walk London.
No booking required; just turn up.
Related website: www.walklondon.org.uk