Music and performance by St Jude's Primary School and Borough Music School to celebrate the 250th anniversary of William Blake's birth.
There is also an art exhibition by Art Adventures at Cathedral School.
"This will be a fantastic opportunity to showcase the talents of 80 Southwark's children and young people," says Borough Music School director Anne Worsley.
"William Blake's visual art and written poetry are usually separated, but he often used them in concert to create a wonderful effect. I am confident that this partnership will also raise the confidence of the young people who are taking part, as well as the spirit of the audience."
Tickets are free but booking essential on firstname.lastname@example.org or 020 7525 9002.