Southwark Bridge Road-based fashion designers and photographers Antoni Burakowski and Alison Roberts are among the locals to be recognised in the 2008 New Year Honours List.
Burakowski and Roberts – better known as Antoni & Alison – each gain the MBE for services to the fashion industry.
They restored a derelict Georgian terraced house in Southwark Bridge Road which now serves as their studio.
Visitors to the Antoni & Alison website can take a virtual tour of 80 Southwark Bridge Road.
Although the couple only bought the house five years ago, their connections with the Borough area go back to their days as students at Central St Martins when they shared a flat in the local area.
Comfort Momoh, a specialist midwife in female genital mutilation (FGM) at St Thomas' Hospital, gains the MBE for services to women's healthcare.
Momoh met the Queen and the Duke of Edinburgh at a reception at Buckingham Palace in November. At the time Momoh said that being invited to Buckingham Palace was a significant recognition of the work she does to research and raise awareness of female genital mutilation worldwide.
"Events like this are very encouraging and promote the work I do with FGM," Comfort said. "I have won many awards but meeting the Queen is a great lifetime achievement."
The MBE is also awarded to SE1 resident Kathleen Carr, a catering supervisor at the House of Commons.
Tate trustee John Studzinski, the millionaire philanthropist who gave £5 million towards Tate Modern's proposed extension, gets the OBE for services to the arts and to charity.