The Canadian Tourism Commission is to move to Bermondsey Square from its current office in Trafalgar Square.
The square – which was recently named best new public space at the London Planning Awards – is already home to a hotel, restaurant, bookshop, supermarket, cinema and gallery.
Bermondsey Square, which had been empty since the Second World War, was redeveloped by the Igloo Regeneration Partnership and completed in 2009.
The Canadian Tourism Commission has taken a five year lease on 2,468 sq ft of office space on the first floor of the development.
"My team and I are particularly excited to be moving to this developing part of London, says Rupert Peters, regional marketing director of the Canadian Tourism Commission.
"As the marketing agency for the promotion of a young, vibrant and modern country we feel we will be re-energised creatively by our new office space and environment. We look forward to meeting our neighbours and to a smooth handover of office operations."
One and a half floors of office space are still vacant at Bermondsey Square. Existing office tenants include Munich Re, architects Purcell Miller Tritton and COW PR.