Detectives investigating the murder of Philip Sherriff at the Pulse nightclub in Blackfriars have released CCTV images of a woman to whom they would like to speak.
Officers believe the woman is a vital witness but they have so far been unable to identify her.
Philip Sherriff, 37, a telecommunications professional from Preston, Lancashire, was assaulted in the Pulse nightclub in the early hours of 4 April. He died in hospital on Easter Sunday 8 April.
A post-mortem examination held on Monday 9 April at Greenwich Mortuary gave cause of death as a stab wound to the neck.
"On the night Mr Sherriff was assaulted the Pulse nightclub was hosting a party on behalf of BlackBerry, and we are aware that large numbers of people attending the event came from outside London," says Detective Chief Inspector Cliff Lyons.
"It is therefore possible the witness we are trying to identify lives elsewhere in the country.
"However, I would appeal for the woman or anyone who recognises her to contact the incident room.
"I would like to reassure anyone who may be worried about contacting the police that they will be treated with the utmost sensitivity."
Detectives are asking anyone with information to call them on 020 8721 4961 or to remain anonymous, call Crimestoppers on 0800 555 111.
For the latest local news and events direct to your inbox every Monday, you need our weekly email newsletter SE1 Direct.
7,000+ locals read it every week. Can you afford to miss out?
Read the latest issue before signing up