Part of Southwark Street was sealed off by police overnight on Friday night after an office building occupied by RBS was damaged in high winds.
Firefighters from Dockhead and Paddington were called to the office block known as 'Bankside 3' after a piece of masonry came loose at the top of the building.
The road remained shut overnight and the M&S Simply Food store was unable to open on Saturday morning due to the precarious position of the cladding above the shop entrance.
The Real Food Market outside the Royal Festival Hall delayed its opening until Saturday afternoon due to "severe wind issues".
For the latest local news and events direct to your inbox every Monday, you need our weekly email newsletter SE1 Direct.
7,000+ locals read it every week. Can you afford to miss out?
Read the latest issue before signing up