Training for Life, the charity which runs the Downside Centre in the Downside Fisher Youth Club building, has gone into administration.
The charity, which is best-known for its Hoxton Apprentice and Dartmouth Apprentice restaurants, specialises in on-the-job training for the long-term unemployed.
The Downside Fisher Youth Club building in Coxson Place off Druid Street was refurbished by Training for Life between 2006 and 2008 under a deal between the two charities which at the time shared a trustee in common.
In return for the £3.2 million refurbishment of the centre, Training for Life was granted a 25-year lease to use the building during the day on weekdays and all day at weekends.
The youth club continued to use the building on weeknights.
The relationship between the two charities has not always been easy and Simon Hughes MP has previously brokered negotiations between the two groups.
Legal notices on the door of the building dated 5 November state that Training for Life's lease on the Bermondsey building has been terminated by the Downside Settlement.
Mazars LLP were appointed as administrators of Training for Life on 8 November.
Training for Life's Barking Apprentice cafe in east London has closed but the Hoxton and Dartmouth restaurants continue to trade at present.
The Downside Fisher Youth Club and Mazars did not respond to requests for comment.