The streets of Bermondsey returned to normality just after 6pm on Tuesday when the World War II bomb found on a local demolition site the previous day was driven away to Kent.
Overnight from Monday into Tuesday police officers knocked on the doors of residents living between 100 metres and 200 metres from the site.
Those in the extended exclusion zone were encouraged to evacuate their homes between 6am and 8am on Tuesday to allow an Army bomb disposal squad to make the device safe.
During the day, evacuees were looked after at a 'rest centre' at Seven Islands Leisure Centre in Rotherhithe.
Bermondsey Health Centre and Artesian Health Centre were also shut for the day.
After hour of painstaking work, at 6pm the bomb was removed from the exclusion zone and driven away by the Army for a controlled explosion at a Kent quarry.
Local Blitz historian Neil Bright believes that the bomb – a 250kg SA German bomb – fell on 11 May 1941 and has lain undiscovered until 2015.
Until recently the site was occupied by Mabel Goldwin House and Evelyn Coyle House – latterly home to the Southwark Irish Pensioners Project.
Southwark Council leader Peter John paid tribute to the emergency services, the Army and volunteers from the British Red Cross and St John Ambulance who contributed to the operation.
Simon Hughes MP said: "These difficult past few days remind us that eternal vigilance is always needed in an area which suffered so much during the blitz.
"Bermondsey has come together again to show real spirit – and I would like to praise the efforts of the emergency services, armed forces, council employees, volunteers and others who have worked so hard.
" I would also like to praise the many Bermondsey residents who coped admirably with such a challenging situation.
"However, there will of course be lessons to be learned. Some people tell me that they feel official communication has not been good enough.
"And I am asking the police, army and local authority to carry out a full review of events from the moment of the first suspicion of any risk to make sure all Londoners learn what can be done better in future."