The private treatment centre on the top four floors of the Cancer Centre at Guy's Hospital opened its doors this week.
The deal with HCA was crucial to the overall funding package for the state-of-the-art £160 million building.
From Monday this week all cancer services at London Bridge Hospital in Tooley Street have been transferred to the new centre which is known as 'London Bridge Hospital, Private Care at Guy's'.
It is equipped with 40 inpatient beds, 9 day surgery beds, a four bed intensive care unit, four integrated operating theatres, Da Vinci robot, 18 chemotherapy bays, x-ray, fluoroscopy, ultrasound and radiotherapy. The centre will specialise in a number of areas including urology, gynaecology and breast surgery.
"We are always working to provide the highest quality care across the London Bridge Hospital campus and the HCA UK group as a whole, so I am proud that this new facility will offer our patients state-of-the-art care and the latest technology in a location that is convenient for them," said Janene Madden, CEO of London Bridge Hospital.
"We are also proud to be associated with Guy's & St Thomas' NHS Foundation Trust, a world leader in advancing medicine and care."
• The Cancer Centre at Guy's has been shortlisted in the London Civil Engineering Awards – details at www.ice.org.uk/londonawards