"More and more business travellers are opting for a budget hotel and last year we generated more sales from business customers than those on holiday," said Peter Gowers, Travelodge chief executive.
"Our new 'SuperRoom' adds an extra choice for customers who are spending more time working in the room, are staying longer or who just value that little bit more comfort.
"Alongside our recently upgraded classic room, this is another important milestone on our journey to become the favourite hotel for value."
The Waterloo Road Travelodge is one of the first four hotels in the chain to offer the 'SuperRoom' which will cost £10-£20 a night more than a standard room in the budget hotel.
The Travelodge London Waterloo was opened by the then Mayor of London Boris Johnson in 2010.
The company recently received permission from Southwark Council to add extra signs to the building.
"We are trying to make the hotel more visible as many customers complain they are going past it without seeing any of the signs," said the company in its application for advertisement consent.
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