Transport for London has launched a public consultation on plans to reroute the 381 bus service via Duke Street Hill in both directions when roads around London Bridge are shut for Network Rail's major station redevelopment.
"To enable Network Rail to continue the development of London Bridge Station they will take possession of St Thomas Street, Weston Street and Stainer Street in January 2013 and these roads would be closed," says TfL on its consultation website.
"Routes 381 and N381 would need to be diverted in both directions as a result.
"In 2018 a new permanent road network will be introduced in the London Bridge Station area. Stainer Street and Weston Street will be closed permanently as they would become part of the redeveloped concourse for London Bridge station.
"A new 24-hour walk route would be created between Tooley Street and St Thomas Street close to the alignment of Stainer Street. There has also been significant development in Tooley Street with more planned for the future. St Thomas Street would re-open but as a one-way street with the direction to be determined at a later date."
The changes also mean that eastbound buses would no longer stop in such close proximity to Guy's Hospital.
TfL is inviting comments from passengers; the consultation closes on Friday 23 November.