Southwark Playhouse has collected prizes in five categories at the Offies, an annual awards ceremony for London theatres away from the West End.
The playhouse is running a donate a seat appeal to help meet the cost of equipping its new premises.
The theatre plans to move back to London Bridge when the major redevelopment of the railway station is complete.
At last week's Offies ceremony hosted by Simon Callow, Southwark Playhouse won more awards than any other theatre:
• Most Promising Playwright for Nicholas Pierpan (You Can Still Make a Killing)
• Best Choreographer for Lee Proud (Mack and Mabel)
• Best Lighting Designer for Richard Howell (The Hairy Ape)
• Best Musical for Floyd Collins
• Special Achievement Award (Southwark Playhouse)
The awards ceremony was organised by theatre website OffWestEnd.com.
Other SE1 winners included Something Very Far Away at the Unicorn Theatre which topped the Best Production for Young People category.
• Southwark Playhouse's new Newington Causeway home was until last autumn occupied by the Hotel Elephant studio and gallery which has now relocated to Brandon Street on the Heygate Estate in Walworth.