Transport for London has published new images showing how the road junctions at Elephant & Castle and Waterloo could be transformed by the removal of the current gyratory systems.
Public consultation on the long-awaited plans for the remodelling of the Elephant & Castle junction begins later this month.
The roundabout at Waterloo's BFI IMAX will also be redeveloped with a new pedestrian area created on the south side of the cylindrical cinema.
TfL claims that its plans will create a better interchange at Waterloo Station as well as improved facilities for cyclists.
"Smarter design of our roads and public spaces, exemplified by our radical plans for Elephant & Castle, will play a key role in ensuring that London remains the best big city to live, work and invest," said Boris Johnson, Mayor of London.
"We've been hard at work putting the bold and imaginative blueprint of the Road's Task Force into practice and we're now seeing the fruits of that labour at key locations across the capital."
Leon Daniels, managing director of TfL's surface transport division, said: "The Roads Task Force was set up to deliver world-class streets and roads fit for the future to support London's population which is set to grow to 10 million people by 2031.
"Balancing the needs of all users, we will be investing millions into transforming London's road network in the coming years, helping to keep the capital moving while creating new, inviting places to work, shop and relax."